"An insightful history of the first hundred years of DNA, Unraveling The Double Helix tells the story one of the greatest triumphs of modern science. Unraveling the Double Helix covers the most colorful period in the history of DNA, from the discovery of "nuclein" in the late 1860s to the publication of James Watson's The Double Helix in 1968. These hundred years included the establishment of the Nobel Prize, antibiotics, x-ray crystallography, the atom bomb and two devastating world wars--events which are strung along the thread of DNA like beads on a necklace. The story of DNA is a saga packed with awful mistakes as well as brilliant science, with a wonderful cast of heroes and villains. Surprisingly, much of it is unfamiliar. The elucidation of the double helix was one of the most brilliant gems of twentieth century science, but some of the scientists who paved the way have been airbrushed out of history. James Watson and Francis Crick solved a magnificent mystery, but Gareth Willia

Assuming the viewer has no background in science, these twelve half-hour lectures cover the fundamental properties of DNA, the techniques that have unraveled its mysteries, the exciting revelations that have come to light, and the stories of the all-too-human scientists involved. Witty and informative, the lectures are delivered by science writer and podcaster Sam Kean, author of the bestseller The Violinist's Thumb.

"Forensic DNA evidence has helped convict the guilty, exonerate the wrongfully convicted, identify victims of genocide, and reunite families torn apart by war and repressive regimes. Yet many of the scientific, legal, and ethical concepts that underpin forensic DNA evidence remain unclear to the general public, judges, prosecutors, defense attorneys and students of law, forensic sciences, ethics, and genetics. Silent Witness examines the history and development of DNA forensics, its applications in the courtroom and humanitarian settings, and the relevant scientific, legal, and psychosocial issues. This book describesthe DNA technology used to compare the genetic profile of a crime scene sample to that of a suspect as well as the statisticalinterpretation of a match. It also reviews how databases can be searched to identify suspects and how DNA evidence can be used to exonerate the wrongfully convicted. Recent developments in DNA technology are reviewed as are strategies for analyzing

This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades. The book begins with a historical overview of the studies on eukaryotic DNA replication by Professor Thomas Kelly, a pioneer of the field. The following chapters include genome-wide studies of replication origins and initiation factor binding, as well as the timing of DNA replications, mechanisms of initiation, DNA chain elongation and termination of DNA replication, the structural basis of functions of protein complexes responsible for execution of DNA replication, cell cycle-dependent regulation of DNA replication, the nature of replication stress and cells' strategy to deal with the stress, and finally how all these phenomena are interconnected to genome instability and development of various diseases. By reviewing the