Describes the principles of gnotobiology- a new science concerned with the effects of microorganisms on germfree plants and animals living in sterile surroundings.

"An international team of biologists, philosophers, and historians of science explores the critically important process of replication in biological and biomedical research. Without replication, the trustworthiness of scientific research remains in doubt. Although replication is increasingly recognized as a central problem in many scientific disciplines, repeating the same scientific observations of experiments or reproducing the same set of analyses from existing data is remarkably difficult. In this important volume, an international team of biologists, philosophers, and historians of science addresses challenges and solutions for valid replication of research in medicine, ecology, natural history, agriculture, physiology, and computer science. After the introduction to important concepts and historical background, the book offers paired chapters that provide theoretical overviews followed by detailed case studies. These studies range widely in topics, from infectious-diseases and en

This book sheds light on a little-known aspect of the Imperial family of Japan: For three generations, members of the family have devoted themselves to biological research. Emperor Showa (Hirohito) was an expert on hydrozoans and slime molds. His son, Emperor Akihito, is an ichthyologist specializing in gobioid fishes, and his research is highly respected in the field. Prince Akishino, Emperor Akihito's son, is known for his research on giant catfish and the domestication of fowl, while Prince Hitachi, Emperor Akihito's brother, has conducted research on cancer in animals. The book shows how they became interested in biology, how seriously they were committed to their research, what their main scientific contributions are, and how their achievements are valued by experts at home and abroad. To commemorate the 60-year reign of Emperor Showa and his longtime devotion to biology, the International Prize for Biology was founded in 1985. The prize seeks to recognize and encourage researches