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1. Comparison of the use of AnaConDa® versus AnaConDa-S® during the post-operative period of cardiac... 2020

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LT-MwEB7xkFZw4K2lPCojcdu1SFOnjiWEBGUrdlcrod0FIS5RbCfqXpKKtH-JIz-CX8aM82gL7IGLlWgmbiOPM_PZM58Bjq2MDXody2UceFxILbiKU8NTrWVHSHQhWs0v5jR13C7Zvd6RdB_qmVq3UFKWpOKEEwKOOH056CAKp_Lwmx9Tpt2wW6IsnD34gZZVpcz7fcx7ozch5ttMyVfbpc4LDdYhqmt5XPIJHXkwm4V_4pgPHd3FDMvjR951A9aqAJWdlxa1CQtJtgWrM7SFW_DpV7Uhvw2P_eYcQ5anDKNJNikSujwdnp1ncT_PLuPTk-HZ8xOjBJBJ8VrA_6CoLJZ0j4_yYszzUVIykjMiYs4tdWicLRtWlIXcjKrfHqi3ejWEemMI722ZhUbP1DVgO3Az-Pa3f8Wrox-4EV1vzBGFpZ62Hc-aXqp0qntKWeX7oU0T1QuIE9qdlS1MIBUpJDK1GBz6sRDaoGPeBeaHRhupe0TaJzAqihHtJ0Z3ESRpHWqvBV_qsY9GJbVHNCVxphGIcAQiNwIRah_U5hFV07yIKL5EgBr4QQuOGjFOUNp1ibMknzgdge4IQ80WfC6tqfk5NE8E2B2UyDk7axSI_Htekv0bOhJwiYEdxsot-Fqb0PRv_f8t9j6mvg8rPq0vuCz1A1gaP0ySQ1giu27Dovx9S-2ddO1F283DNixf9b8P7vHup-TYXgf3L5l-MV8

   Marcos-Vidal, Jose Miguel; Merino, María; González, Rafael; García, Cristina...

   Journal Of Clinical Monitoring And Computing, Vol. 34, Issue 1, pp. 89 - 95.

   Changes have been made to the AnaConDa device (Sedana Medical, Stockholm, Sweden), decreasing its size to reduce dead space and carbon dioxide (CO 2 ) retention. However, this also involves a decre... Read more

   Changes have been made to the AnaConDa device (Sedana Medical, Stockholm, Sweden), decreasing its size to reduce dead space and carbon dioxide (CO 2 ) retention. However, this also involves a decrease in the surface area of the activated carbon filter. The CO 2 elimination and sevoflurane (SEV) reflection of the old device (ACD-100) were thus compared with the new version (ACD-50) in patients sedated after coronary artery bypass graft surgery. After ERC approval and written informed consent, 23 patients were sedated with SEV, using first the ACD-100 and then the ACD-50 for 60 min each. With each device, patients were ventilated with tidal volumes (TV) of 5 ml/kg of ideal body weight for the first 30 min, and with 7 ml/kg for the next 30 min. Ventilation parameters, arterial blood gases, Bispectral-Index™ (BIS, Aspect Medical Systems Inc., Newton, MA, USA), SEV concentrations exhaled by the patient (SEV-exhaled) and from the expiratory hose (SEV-lost) were recorded every 30 min. A SEV reflection index was calculated: SRI [%] = 100 × (1 − (SEV-lost/SEV-exhaled)). Data were compared using ANOVA with repeated measurements and Student’s T -tests for pairs. Respiratory rates, tidal and minute volumes were not significantly different between the two devices. End tidal and arterial CO 2 partial pressures were significantly higher with the ACD-100 as compared with the ACD-50. SEV infusion rate remained constant. SEV reflection was higher (SRI: ACD-100 vs. ACD-50, TV 5 ml/kg: 95.29 ± 6.45 vs. 85.54 ± 11.15, p = 0.001; 7 ml/kg: 93.42 ± 6.55 vs. 88.77 ± 12.26, p = 0.003). BIS was significantly lower when using the higher TV (60.91 ± 9.99 vs. 66.57 ± 8.22, p = 0.012), although this difference was not clinically relevant. During postoperative sedation, the use of ACD-50 significantly reduced CO 2 retention. SEV reflection was slightly reduced. However, patients remained sufficiently sedated without increasing SEV infusion. Read less

   Journal Article  |  Full Text Online

2. The Italian Multicentre Registry of Fenestrated Anaconda™ Endografts for Complex Abdominal Aortic... 2020

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8QwEA6ygnjxDb6J4E2KbZM2LYhQxGUX0YPowVPI03XR3WUfonj1l_jT_CVO0hZXUBGPhTZtM9OZ-Zov3yC0r5lQkHV0wEQSBpRJGuTCqsBKySLKIIXI_OvPnHKz-uibJXxPxTLdR6esHYdelZRAxJ2FxJMC1pot2meti09OR9lREyCN206U0WqXzPej_JSJpmNyXCWa5iK6qR_R80tcV4Npov2hFzf0iha1kOOfX2cJLVTVJy5Kd1lGM6a3gubOq_X1VfQCXoPbY__vA_u9uZ68afClufVt4XDf4qYLj17UVuOjznHRg6AKwP7osHP8_vqGT3vaUb7seIShIMYu4NybJ1xI3fcNxHDRd7fHhZPSfB49jGDwgbgbrqHr5unVSSuo2jMEihAyDmLL0tQSwEN5YkRkGAtTFcY6IlbLJNOGpJFIc2aVCommrqOZiVgW2VwykSaarCMcZ0oqJlMnrEehchGAyI2SBICMlJkMN9BBbSM-KOU3eM1L63I3kdxNJA8ph4ncQEltRl4VEGVhwMEIv163V9ucw9fllkxEz_QncBKNAX1QgF2b_xx7C827o5IzuI0a4-HE7KCG85vdyn0_AG1279A

   Pini, Rodolfo; Giordano, Jacopo; Ferri, Michelangelo; Palmieri, Bruno...

   European Journal Of Vascular And Endovascular Surgery, Vol. 60, Issue 2, pp. 181 - 191.

   The aim was to describe the outcomes of the Anaconda™ Fenestrated endograft Italian Registry for complex aortic aneurysms (AAAs), unsuitable for standard endovascular aneurysm repair (EVAR). Betwee... Read more

   The aim was to describe the outcomes of the Anaconda™ Fenestrated endograft Italian Registry for complex aortic aneurysms (AAAs), unsuitable for standard endovascular aneurysm repair (EVAR). Between 2012 and 2018 patients with a proximal neck unsuitable for standard EVAR, treated with the fenestrated Anaconda™ endograft, were prospectively enrolled in a dedicated database. Endpoints were peri-operative technical success (TS) and evaluation of type Ia/b or 3 endoleaks (T1/3 EL), target visceral vessel (TVV) occlusion, re-interventions, and AAA related mortality at 30 days, six months, and later follow up. One hundred twenty seven patients (74 ± 7 years, American Society Anesthesiology (ASA) II/III/IV: 12/85/30) were included in the study in 49 Italian Vascular Surgery Units (83 juxta/para-renal AAA, 13 type IV thoraco-abdominal AAA, 16 T1aEL post EVAR, and 15 short neck AAA). Configurations with one, two, three, and four fenestrations were used in 5, 56, 39, and 27 cases, respectively, for a total of 342 visceral vessels. One hundred and eight (85%) bifurcated and 19 (15%) tube endografts were implanted. In 35% (44/127) of cases the endograft was repositioned during the procedure, and 37% (128/342) of TVV were cannulated from brachial access. TS was 87% (111/127): five T1EL, six T3EL (between fenestration and vessel stent), and six loss of visceral vessels (one patient with a Type Ia EL had also a TVV loss) occurred. Thirty day mortality was 4% (5/127). Two of the five T1EL resolved spontaneously at 30 days. The overall median follow up was 21 ± 16 months; one T1EL (5%) occurred at six months and one T3EL (4%) at the three year follow up. Another two (3%) TVV occlusions occurred at six months and five (3%) at three years. The re-intervention rate at the 30 days, six months, and three year follow up was 5%, 7%, and 18 ± 5%, respectively. The fenestrated Anaconda™ endograft is effective in the treatment of complex AAA. Some structure properties, such as the re-positionability and the possibility of cannulation from above, are specific characteristics helpful for the treatment of some complex anatomies. Read less

   Journal Article  |  Full Text Online

3. Wash-in kinetics for sevoflurane using a disposable delivery system (AnaConDa) in cardiac surgery... 2009

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1JSwMxFA4uFy-iKO6SgwelhM50lsyACO4L3tSzvKQJrbbTyqjgj_G_-jJJ2nFDxctQEjqEeV_elve-ELLV5iDR6rQZhyRgMRcxy0FLpoXgYczRhIj8QzLn1ffCfFnF3vy3aHEMhWtaZf8g3tFLcQB_o5DxiWLG568Eba5DYt2icY_-YsW5bAoH0d4NdO8JDZFqPFXpADBnMcNB6VqleqYe48URORs3c7-Aw0FxBCZNYGrTK-TIRmnbpj3_avnuENgRItXYJ6AANDMdVXahSjYcjBFyZc4qStfgddkY5XYuBh00l268dt0xrtGPjisNoNe_f-7aPpXTdxmLvFbooqyWRYvIUm7vXhmp4aBVw1tcU6qxvVrkk7K3RFjiDow9U8PA6t6ayIf9SuYmxjSR4s-zH6i3_dQkmUS9Znzt85PRERVGJYnnu82jJi6jaRdR8dDaP9Zjlcj5LNdzZNYFG3TfgmaeTKhigTw4wFAPGIqAoTXA0AowFOgYMNQDhlrA0O3dzp5HzG6zs7dD8YUOM9RhhnrMLJKbk-PrwzPmLt5gEh3gRyZSCUmKdlJmuIVTqaKwraXUWgNGC1kCOSRhlMow4-0A97hWCbrVXMosFSGGEK1lQluZFJKL1FAmxuiTAs8yJUWEIaoQmQhWyJL9NLdDS6ty6z_a6rcza2RmjKd1Mq1xC6sNMmX0xGYlnTcOf2ar

   Sturesson, L W; Johansson, A; Bodelsson, M; Malmkvist, G

   British Journal Of Anaesthesia : Bja, Vol. 102, Issue 4, p. 470.

   The use of volatile anaesthetics has increased in situations where conventional anaesthetic machines are inadequate or unavailable, for example, cardiac surgery and intensive care. The disposable a... Read more

   The use of volatile anaesthetics has increased in situations where conventional anaesthetic machines are inadequate or unavailable, for example, cardiac surgery and intensive care. The disposable anaesthetic conserving device, AnaConDa, allows vaporization of liquid volatile anaesthetics from a syringe pump and rebreathing of exhaled anaesthetic. Clinical use requires understanding of device-specific anaesthetic agent kinetics, which are not fully known. We compared the wash-in kinetics for sevoflurane administered by a conventional vaporizer in a non-rebreathing system and the AnaConDa and evaluated if a standard anaesthesia gas monitor gave accurate readings while using the AnaConDa. Cardiac surgery patients were randomized to maintenance of anaesthesia with sevoflurane either via a vaporizer or via the AnaConDa (n=8 in each group). Sevoflurane in arterial blood and airway gas was measured with gas chromatography and standard gas monitoring. The initial increase in arterial sevoflurane tension was greater with the vaporizer than with the AnaConDa, but the time to reach 80% of maximum sevoflurane tension was close to 8 min in both groups. End-tidal sevoflurane tension mirrored arterial tension in both groups, whereas measured inspired tension was lower than expired and arterial tensions with the use of the AnaConDa. The wash-in kinetics for sevoflurane delivered by the AnaConDa are similar to a vaporizer. End-tidal sevoflurane tension accurately reflects arterial tension whereas inspired tension may be underestimated using an AnaConDa. Read less

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