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1. Effect of Virtual Reality Training on Balance and Gait Ability in Patients With Stroke:... 2016

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELfY9sIL40tQKJVBMJ6i5qu2w1tbrdskxkpbBtqL5TjOKEjJ1KYPiH-eOzupFoFYVemqKr9Ebu98H-75Z0LeKiYSlgjtqVDFXsyY8ZQwiZergYGQY3Ruj064tZjjCkXcC1Prt3GL1ldnpcZl8j6EliROInjtkQMISzFa8eh4vPW8kF27dDfCtoMwco3uIaQY_ZvqB_ZxMUxRWiGodsSt3W1_JZk22EwOyVUzTNtjgicb3G6271uCQ8tq0ZA57v6VHpIHdQpKh85mHpF7pnhMDqe1wujC8Qw8Ib8dszEtc3q5XOE-EzozNm2ni_pgCVoWdITNkdpQVWT0RC0rOrT9tr_osqBTx9q6pl-X1Xc6r1blT_OBzrfs0dT9NWHvPTeV8hqOlKfky-R4MT716rMaPM2SoPJMNghNDOWkn7Iw5jwNVJaYKI-EYMxXhuMh11zoRIGLUYngapD6OZSnQossCFT0nNCcZXmQBmGKayza12nCszyG94FhUWxUh7xr9CZvHBeHhBoG9StBv7LRb4ccoVIl0lsU2D-j3RqMhAGPL-QwhhIqRN7ADnnTBl6rzXotxcnHu0Fn80-7gGYt0PsalJfVSmlV74AoC4MkXC3kUQt57SjI_wXstoDgG3TrMgW7vuPH6jaWKWv3tZZglgH3IZNmHfJ6exkfji15hSk3iIHcDntR-f8wjXl3yDM3obaDCTlMVyhoX-xw90tyH8fr2oi6ZL9abcwrso8Tr0f2-OyzlZcov3ErRz3rGnrk4HR8NrmCT-f-zMoFyvDCyukfAMxj2Q

   de Rooij, Ilona J.M; van de Port, Ingrid G.L; Meijer, Jan-Willem G

   Physical Therapy, Vol. 96, Issue 12, pp. 1905 - 1918.

   Abstract Background Virtual reality (VR) training is considered to be a promising novel therapy for balance and gait recovery in patients with stroke. Purpose The aim of this study was to conduct a... Read more

   Abstract Background Virtual reality (VR) training is considered to be a promising novel therapy for balance and gait recovery in patients with stroke. Purpose The aim of this study was to conduct a systematic literature review with meta-analysis to investigate whether balance or gait training using VR is more effective than conventional balance or gait training in patients with stroke. Data Sources A literature search was carried out in the databases PubMed, Embase, MEDLINE, and Cochrane Library up to December 1, 2015. Study Selection Randomized controlled trials that compared the effect of balance or gait training with and without VR on balance and gait ability in patients with stroke were included. Data Extraction and Synthesis Twenty-one studies with a median PEDro score of 6.0 were included. The included studies demonstrated a significant greater effect of VR training on balance and gait recovery after stroke compared with conventional therapy as indicated with the most frequently used measures: gait speed, Berg Balance Scale, and Timed “Up & Go” Test. Virtual reality was more effective to train gait and balance than conventional training when VR interventions were added to conventional therapy and when time dose was matched. Limitations The presence of publication bias and diversity in included studies were limitations of the study. Conclusions The results suggest that VR training is more effective than balance or gait training without VR for improving balance or gait ability in patients with stroke. Future studies are recommended to investigate the effect of VR on participation level with an adequate follow-up period. Overall, a positive and promising effect of VR training on balance and gait ability is expected. Read less

   Journal Article  |  Full Text Online

2. A Comparison and Catalog of Intrinsic Tumor Growth Models 2014

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3dS-QwEB9ORTgf9M47tH4sObink9zZpEmbx7W4px4HwimILyVNEwS1K-4uuP-9k3Rbd_F88CWBNiRtZiYzmUnmB_Bdy0xJlRmqmU5oIqWlOrOKOi0sqhxrXIBOmHPmAOtcF_XtzzYiGRbql7tuQTbRoqe4Q5B0ugQrAnWfRy3ILs-61Rf5rTF5FUo6qqs2kvm_LhZ10SsDczE4ymY6Z7DRAKuOQqrC4ZO_jbRw5v5XyHMYklvM5XR8x599gvWZNUr6Dft8hg-23oTVBp9yuglrf7ukrqMvoPok71ALia4rkje-HzJ05LQe46BIcnIxuR8-kt-4vR_fEA-1djf6CpeD44v8hM6QF6gRnI1pFRtW8Uo5YxhPGZeikobb0jmpOZeHVSqtEkIwqU1cokJLs9h6vGpUhAZNLL4NxMnKxWXMSu8xMYemVGnlEqyFlTyxOoIf7eQXD01mjeIlh7KfkgKnpPBTUkwj2GvJU8yEbFT4iGqiPDZ5BN-61ygePuahazuc-DY-7ot2JItgqyFrNxpafxlakGkEBy1h5jp_61N23tV6Fz4yT9lwZHAPlsePE7sPy55XerCUXqWhPOoFJu7BSv_oLB9gfZKfDq7x6Z-U9vx51PNQ_sPyXFw_A03E8J4

   Sarapata, E. A.; de Pillis, L. G.

   Bulletin Of Mathematical Biology, Vol. 76, Issue 8, pp. 2010 - 2024.

   Determining the mathematical dynamics and associated parameter values that should be used to accurately reflect tumor growth continues to be of interest to mathematical modelers, experimentalists a... Read more

   Determining the mathematical dynamics and associated parameter values that should be used to accurately reflect tumor growth continues to be of interest to mathematical modelers, experimentalists and practitioners. However, while there are several competing canonical tumor growth models that are often implemented, how to determine which of the models should be used for which tumor types remains an open question. In this work, we determine the best fit growth dynamics and associated parameter ranges for ten different tumor types by fitting growth functions to at least five sets of published experimental growth data per type of tumor. These time-series tumor growth data are used to determine which of the five most common tumor growth models (exponential, power law, logistic, Gompertz, or von Bertalanffy) provides the best fit for each type of tumor. Read less

   Journal Article  |  Full Text Online

3. A cellular automata model of tumor–immune system interactions 2006

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV27TsMwFL1CRUgsvAXlUTywIYskdpxkQuVRFSExwcBkOYktUYkWtcnAxj_wh3wJ13aidigIMSVDHva1k3vu8wCcKZFmIksLqiLFKRdCU5XqjBoVa1Q5ujCOOmHBmeOL1WdLQvguFWuElnzj_nCZj_jHZXFiiRoGN1fzFrvcEQK6_HSLS5oSmeWP-EkNLYWZrFE3g014bgfqskwst8Fiuv2Fa3Ho-lq07Rz_PKkt2GgwKOn7TbMNK3q8A2uelfJ9Fy77xLrzbX4qUXU1QUyriGPMIRNDqvp1Mv36-HyxhSWa-E7QxHadmPoaidkePA1uH6-HtOFZoAVLkopGJi6jBKGDSk3GFJo0ZRiY0KSZDjgvRWlyrWw4EM1lxGsGEaXQjMVG69QwPD0AYvCqMA-j3PpHiqDIs6Q0HI-xFoxr1YXzVt7yzffRkG2C2UhaWVhCzFhaTswg6kLcLolskIDX8BLl-Ot9p-36SfxMrLDUWE_qmRQ4PzSewi7s-2Wdj0LYSGEoDv_5ziNY924ZToPkGDrVtNYn0LFboger_bv74UPPbdRvgDzlZg

   Mallet, D.G.; De Pillis, L.G.

   Journal Of Theoretical Biology, Vol. 239, Issue 3, pp. 334 - 350.

   We present a hybrid cellular automata–partial differential equation model of moderate complexity to describe the interactions between a growing tumor next to a nutrient source and the immune system... Read more

   We present a hybrid cellular automata–partial differential equation model of moderate complexity to describe the interactions between a growing tumor next to a nutrient source and the immune system of the host organism. The model allows both temporal and two-dimensional spatial evolution of the system under investigation and is comprised of biological cell metabolism rules derived from both the experimental and mathematical modeling literature. We present numerical simulations that display behaviors which are qualitatively similar to those exhibited in tumor–immune system interaction experiments. These include spherical tumor growth, stable and unstable oscillatory tumor growth, satellitosis and tumor infiltration by immune cells. Finally, the relationship between these different growth regimes and key system parameters is discussed. Read less

   Journal Article  |  Full Text Online

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