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1. Ten Years Experience of In-Center Thrice Weekly Long Overnight Hemodialysis 2009

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV07T8MwED7RDogF8RKEpwcY3Sax8_CIKipeBYYyMEX22YGiNkW0_f_YeVCKmJiTKNHnc7473913AOdKWw5KmabapD7lRqZUBnlOFY90LBPNGKrVwxyIml6Ysmgf1ahTjCedYvRW1lZ-TLDb1Il1nwa9ME6F3RzdFrQSxpsQvfr9cs7KSauWJyMqfB5U1e6hpbZu7_ah41INQeiXc_oEd0k-sUpJjUzwXy7n78rJH1TU34LN2ockl9W3bsOaKXZgfVBnyXfhbmgK8mJNeEaWSsZkmpObgrrTXPNJhm9OTIhUevrkflq8kkc3dNeF6uTaTKaun8SJlezBc_9q2Lum9dAEijzgc4pGoPYN42msDdMRhkkofRYptDs7yaXgSqBEFxSrPAm0RQhVIDDFMBdaGHYARMiU-VJqFvCII0tEgpbV0fjKchmXsQcXDWDZRyWKkdlgwmGcWYyzBmMPSINmNpvI8diCF2b4LmcFz-Iy-e3BWYNyZg3bZStkYaaLmSs4s85DHHiwX2G-fFW9bh4kK6vxfYOTzF69Yi2plM6uLefw308ewUaVT3LnMMfQnn8uzAm0Xb_FaWmHX4EL420

   Powell, Joanna Ruth; Oluwaseun, Oyeniran; Woo, Yook Mun; Padmanabhan, Neal...

   Clinical Journal Of The American Society Of Nephrology, Vol. 4, Issue 6, pp. 1097 - 1101.

   Published studies suggest that longer hemodialysis (HD) sessions are associated with improved morbidity and mortality, but few centers offer long sessions. The Western Infirmary renal unit has offe... Read more

   Published studies suggest that longer hemodialysis (HD) sessions are associated with improved morbidity and mortality, but few centers offer long sessions. The Western Infirmary renal unit has offered long overnight hemodialysis (LOH) (6 to 7 h) thrice weekly since 1998. The aim of this study was to describe patients who chose LOH and compare outcomes with patients on conventional hours (4 to 5 h) HD. Patients who ever had LOH for three or more consecutive sessions were identified (n = 146). Indices of urea reduction ratio (URR), anemia, hyperphosphatemia, and predialysis BP (BP) control in a subgroup of all patients on LOH for at least 1 yr since 2004 were compared with age, sex, and diabetes-matched controls undergoing conventional duration HD. The mean age at the time of starting LOH was 51.8 yr and 74.7% started with a functioning arteriovenous fistula. Median duration of continuous LOH was 1.6 yr. Of those no longer on LOH, only 33.3% reverted to conventional hours HD (mean duration LOH 2.2 yr). When comparing LOH and conventional HD cohorts, there was increased URR and mean hemoglobin with a trend toward lower mean erythropoietin index. There was a trend toward fewer phosphate binder tablets but no difference in mean serum phosphate, BP, or number of prescribed antihypertensive medicines. LOH is a well tolerated hemodialysis option, associated with improved URR and better control of anemia. Read less

   Journal Article  |  Full Text Online

2. Protection of encapsulated human islets implanted without immunosuppression in patients with type... 1994

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1fb9QwDI_Y0Ka9IBigAQP5gbept2uTXttHtD-iEohJGxJvU9Km0knj7rQy8WH4Tnwm7NptwzEm0F6qKEmj1P7JsV3bUeqtq_EMynUd1T6fRsbbPLJx00TOpPXMZrXWlVtz5vzsc2FujWI_vDdrsQ-ZS6my_8HeYVHswDYyGZ_IZnz-E6PPuNKCKH64M4uG75UlTZIv4Ju3yJuW8iGviIwcbk7hyHPKDVm2NysJhu2CHqXQaht4aEsKWudWOTpruWzTwWK54K55NcS9tzeO3DttqPkeB07e9et_AnfEOaWBdXfmHR-M7p_vts9RC_5jfSLfY4fPse-D_cbq8JkkrtWS4WeGiK1BSMcJVU3lc9izXC50Eekk-xIKbq7vJAAtAilM_5ZuOx4S3RUYIKpMjJ4Uk_WJyNnV1w4nOYrCGZ8Mdw6uFeuWkQ21gYKQlPPydNAL0FTkhCj5PC4hSns6_H1HO2pL1gltnUR0novH6pEYK_COQfdEPfCLXbX9UcIxnqofI_Zg2UCIPeiwB4w9GLAHgj34A3swX0CPvW4WEOKghOW1tErosQeIPZofYA8Ee9Bj75n6fHpycfQ-kts-okrHaRYVTiepqXycm8LFFVoCzrqY3BVZMssLrxudZrXLTYU2RkJ2cjVF5Tv2Jk0Th4bKnoLC5npqba1jg0tpJDKuoys_xdcyY2cv1HOm5-WKa7lcCqFf_m3gldoZMbqvHjYoNfxrtUmi6U3H31-DuIsv

   Scharp, D W; Swanson, C J; Olack, B J; Latta, P P; Hegre, O D; Doherty, E J...

   Diabetes (New York, N.Y.), Vol. 43, Issue 9, p. 1167.

   Human islets were macroencapsulated in permselective hollow fiber membrane devices and successfully allotransplanted subcutaneously with > 90% viability after 2 weeks in situ. Recipients were patie... Read more

   Human islets were macroencapsulated in permselective hollow fiber membrane devices and successfully allotransplanted subcutaneously with > 90% viability after 2 weeks in situ. Recipients were patients with type I or type II diabetes and normal control subjects; none was immunosuppressed. Between 150 and 200 islet equivalents were implanted in each of the nine patients. No adverse patient complications were observed. Biocompatibility of devices was excellent. Insulin-positive beta-cells were confirmed in encapsulated islets recovered from the implanted devices in all patient populations including the type I diabetic patients. Glucose-stimulated insulin release could be demonstrated in vitro from recovered islets. These data demonstrate that macroencapsulated human islets can survive at the subcutaneous site and that permselective membranes can be designed to protect against both allogeneic immune responses as well as the autoimmune component of type I diabetes. Read less

   Journal Article

3. Development of a web-based genetics institute for a nursing audience 2004

   https://ncsu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3fT9swED5Bq0l72YBNIysUP-zVNK3d2Hma0tIKJJCmDRhvln8kT4jCgP9_d4mTdkjshT5YbR2rbu58951z_g7gmwvog7QIPJQ65bK0mttxVXEnpyGzKgjh3b-bOetT_FG-rVmsbXVYedomH6Enwxfi5e_3D5zqRtHz1VhEYxv6RP416UG_OP91fra2xjrVLWM4GmPZnOJBVKBH3Xe1qqToGTkdpN3wTy-t9Cb2FNEHLT_CbTv7OvWECh5s5uCPat7Dmuyi5Xh8yz_dgQ8Rq7KiUa5d2Crv9qjMc0wJ2YN3ca_hE5xsJB-xVcUs-106PkMXGRgxWxMZNOsSExgiZbwkjmYFpTKi8n2Gq-Xicn7KY4EG7hEVPnExDaLKicEsVHosp9opkUl8a0XltUfoMcl8OfZ55ioMdazIrA8yd1OMyZWTqdgHlluNPTYIHC-9ULnyiCB8mTr0m9JmCRy38jD3DQGHwcCFBGhIgIYEaFoBYlcCRyQ105wj7RawKTJNXIiTVCUwaO-6iSv20XS3HMd3vbjU6PmJvStXz48mw1kjYBYJsFeuUBjNCYmIKIEvjaKs54yhIXEjfv3vjw_gfZMaRElsB9B7-vNcHkKPVGkI2-rnNbU3qm5nw6jr-Gm2mGN7kf74Cy0oA2A

   Prows, Cynthia A; Hetteberg, Carol; Hopkin, Robert J; Latta, Kathy K...

   The Journal Of Continuing Education In Nursing, Vol. 35, Issue 5, pp. 223 - 231.

   The purpose of this article is to serve as a resource for readers considering the development of a web-based continuing education offering in their particular specialty areas. A theory-based instru... Read more

   The purpose of this article is to serve as a resource for readers considering the development of a web-based continuing education offering in their particular specialty areas. A theory-based instructional design using a face-to-face genetics summer institute as a content template and incorporating several levels of planned formative evaluation are described. Summative evaluation strategies revealing satisfaction with the format, improved knowledge, and ability to use genetics knowledge in participants' work setting are also discussed. Finally, lessons learned following completion of two 18-week web-based genetics institutes are shared. Read less

   Journal Article  |  Full Text Online

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